Bennett discounted this theory citing laboratory evidence that demonstrated no excess exposure to salicylates among the patients who participated in the study.
He further argued that Dr. Beyond this study, there is only one other study that provides evidence documenting the use of guaifenesin to treat fibromyalgia. In this study, female fibromyalgia patients and healthy control subjects completed telephone surveys regarding their history of medication use. Among the fibromyalgia patients, In their discussion of the survey results, the researchers point out the fact that their study gained popularity with an Internet-based fibromyalgia discussion group that advocates the use of guaifenesin therapy, and as a result their findings related to guaifenesin were likely biased.
Furthermore, the researchers cite the guaifenesin therapy protocol promoted by Dr. Amand, as well as anecdotal evidence from patients that attests to the efficacy of such therapy, however they make a point to mention that there are no published controlled studies related to guaifenesin therapy in the scientific literature Shaver et al. Amand RP, Marek C. The use of uricosuric agents in fibromyalgia: theory, practice and a rebuttal to the Oregon Study of Guaifenesin Treatment.
Clin Bull Myofascial Ther. Available atAccessed April 18, London M. The truths and myths of the use of guaifenesin for fibromyalgia or Guaifenesin: one medicine, several effects. Bengtsson A, Henriksson KG. The muscle in fibromyalgia: a review of Swedish studies. J Rheumatol. Reduced high-energy phosphate levels in the painful muscles of patients with primary fibromyalgia. Arthritis Rheum. Rheumatology Oxford.
Use of P magnetic resonance spectroscopy to detect metabolic abnormalities in muscles of patients with fibromyalgia. Lack of association between fibromyalgia syndrome and abnormalities in muscle energy metabolism. In vivo 31P magnetic resonance spectroscopy MRS of tender points in patients with primary fibromyalgia syndrome. Rheumatol Int. For the reasons you listed out! A person with fibromyalgia may be able to clean the house, go shopping and do yard work on Monday, but on Thursday they may not even be able to get out of bed.
Want to know why? Be healthy — Get inspired and make your life beautiful. Taking control of your fibromyalgia is possible! Today we are going to look at one of the most common medical treatments available Guaifenesin.
According to drugs. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth. Guaifenesin is used to reduce chest congestion caused by the common cold, infections, or allergies.
Do not use it in larger amounts or for longer than recommended. Do not give guaifenesin to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child.
Death can occur from the misuse of cough and cold medicines in very young children. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Well there might be some side effects such as dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.
Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue ; difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.
Because it helps get rid of uric acid, guaifenesin was chosen in the s for the experimental guaifenesin protocol — a treatment for fibromyalgia. Proponents of the guaifenesin protocol believe that it treats fibromyalgia by removing excess phosphate from the body. Could taking a medication that eliminates phosphates from the body be useful? If the phosphates are the underlying cause of the Fibromyalgia symptoms then yes.
The protocol was based on his belief that phosphate deposits throughout the body were the cause of fibromyalgia and that fibromyalgia symptoms could be reversed by removing excess phosphates from the body, which he said guaifenesin would do.
Amand began to formulate his phosphates theory when one of his patients, who was taking medication for gout, demonstrated how he could scrape tartar calcium phosphate off his teeth with his fingernail. Amand speculated that some mutant gene may be interfering with adequate urinary excretion of phosphates.
If that were true, it could cause a system-wide retention of phosphates, which would seriously affect the mitochondria the energy producers in each cell of the body. The resulting cellular fatigue could cause the kind of body-wide malfunctions found in fibromyalgia. At first, Dr. Amand tested his theory by prescribing gout medication for his fibromyalgia patients.
Over the years, however, he has fine-tuned his approach to fibromyalgia treatment. He says he no longer prescribes gout drugs uricosurics , but instead uses guaifenesin exclusively because side effects are rare , there are no known drug interactions, and it is even safe for children. Following the guaifenesin protocol for fibromyalgia is not for the faint of heart. Following are the two primary challenges of the guaifenesin protocol:.
Salicylates block the benefits of guaifenesin for fibromyalgia — Salicylates are derivatives of salicylic acid that occur naturally in plants and can be found in many medications, supplements, cosmetics, personal care products, topical medications, creams, lotions and gels, etc.
It is essential that anyone taking guaifenesin for fibromyalgia avoid using any products containing salicylates. Because tea is a particularly strong blocker for people with fibromyalgia, Dr.
Amand also recommends you drink no tea of any kind. The Herxheimer Reaction — People on the guaifenesin protocol usually experience an intensification of fibromyalgia symptoms at first; then as phosphates are cleared from the body, the symptoms gradually improve.
Simply put, you get worse before you get better. This is sometimes referred to as a Herxheimer Reaction or herxing.
While clearing phosphates from the body is not exactly the same thing, what the patient experiences is very similar. According to Dr. Amand, this worsening of symptoms is a key part of the protocol.
In fact, it is how he determines when the correct dosage of guaifenesin has been reached. Sometimes patients may even experience new symptoms, but he stresses that these are not side effects; rather they are a signal that the guaifenesin is working.
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